No, paint does not adhere to a silicone sealant.
To achieve an interior paintable sealant joint, it is important to use a good quality acrylic sealant. When using Painters Flexible Caulk you can effectively fill and seal window frames and sills, door frames, skirting boards and architraves. The sealant joint can then be easily painted over once cured.
Alternatively, you can also use a hybrid polymer sealant such as Fix ALL Flexi. Perfect when higher flexibility is required, or for applications areas prone to high humidity - bathrooms and kitchens. You can paint over this product with most paints.